You can easily combine two ranges with Union, you can get their common parts with Intersect - but if you need to get all cells which are in Range1 but not in Range2:


Sub test()
Dim v As Variant
For Each v In sbRLess(Range("A1:D4"), Range("B2:C3"))
    Debug.Print v.Address
Next v
End Sub

will result in


Appendix – sbRLess Code

Please read my Disclaimer.

Option Explicit

Function sbRLess(r1 As Range, r2 As Range) As Range
'Returns all cells in r1 which are not in r2.
'Can return a multi-range.
'Source (EN): http://www.sulprobil.com/sbrless_en/
'Source (DE): http://www.bplumhoff.de/sbrless_de/
'(C) (P) by Bernd Plumhoff 06-May-2020 PB V0.30
Dim v As Variant, r As Range, r3 As Range
Dim bFirst As Boolean
Set r3 = Application.Intersect(r1, r2)
If r3 Is Nothing Then
    Set sbRLess = r1
    Exit Function
End If
bFirst = True
For Each v In r1
    If Application.Intersect(r3, v) Is Nothing Then
        If bFirst Then
            Set r = v
            bFirst = False
            Set r = Application.Union(r, v)
        End If
    End If
Next v
Set sbRLess = r
End Function